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WhatIsLCA
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LCA3

SPATA7

Spermatogenesis-associated protein 7; involved in ciliary function in photoreceptors

No Targeted Treatment Yet

Chromosomal Locus

14q31.3

Inheritance

Autosomal Recessive

Frequency

~3% of LCA cases

OMIM #604232

Key Clinical Features

  • 1Severe visual impairment from infancy
  • 2Ciliopathy-related photoreceptor degeneration

Sources: