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WhatIsLCA
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LCA9

NMNAT1

Nicotinamide nucleotide adenylyltransferase; essential for NAD biosynthesis in photoreceptors

No Targeted Treatment Yet

Chromosomal Locus

1p36.22

Inheritance

Autosomal Recessive

Frequency

<1% of LCA cases

OMIM #608553

Key Clinical Features

  • 1Severe macular atrophy (macular coloboma-like lesion)
  • 2Vision loss from infancy
  • 3Progressive macular degeneration is characteristic

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